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Alternative Splicing Gallery

Detail view for swissprot protein HDAC8_HUMAN and isoform Q9BY41-2

Template: 1t64
Sequence Identity (Template - Swissprot): 1.0
Coverage of swissprot protein: 0.9655172

Alignment

HDAC8_HUMAN	MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
1t64		-------------LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
SSE		-------------CCCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHCEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEC
VARSPLIC	                                                                                                    

HDAC8_HUMAN	DCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
1t64		DCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
SSE		CECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCECCECECCECCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEE
VARSPLIC	                                                                                                    

HDAC8_HUMAN	HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
1t64		HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
SSE		EECCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCECCCCCCCCCECHHHHHHHHHHHHCCCCEEEE
VARSPLIC	                                               RRRRRRRRRRRRRRRRRRRRRRRRRDDDDDDDDDDDDDDDDDDDDDDDDDDDD

HDAC8_HUMAN	LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
1t64		LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
SSE		ECCCCCCHHHHHHHHHHHHHHHHCCCCCCECCCCCCHHHHCCCCECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

Varsplic events:
VSP_007177 REMOVE 273-377, affected aminoacids in template: 259-363 Color: Red
VSP_007176 REPLACE 248-272 LKEVYQAFNPKAVVLQLGADTIAGD => RTSCPKSRPVEAAAAACLPHLHSLV, affected aminoacids in template: 234-258 Color: Green

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