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Alternative Splicing Gallery

Detail view for swissprot protein SIRT2_HUMAN and isoform Q8IXJ6-4

Template: 1j8f
Sequence Identity (Template - Swissprot): 1.0
Coverage of swissprot protein: 0.80205655

Alignment

SIRT2_HUMAN	MAEPDPSHPLETQAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKERLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPS
1j8f		---------------------------------GEADMDFLRNLF-----------RLLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPS
SSE		---------------------------------CHHHHHHHHHHC-----------CCCCCCCHHHHHHHHHCCCCCCEEEEECHHHCHHHCCCCCCCCC
VARSPLIC	                                                                                                    

SIRT2_HUMAN	TGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASC
1j8f		TGLYDNLEKYHLPYPEAIFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQEDLVEAHGTFYTSHCVSASC
SSE		CCCCCCCCCCCCCCHHHHHEHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCHHHEEECCEEEEEEEECCCCC
VARSPLIC	                                                                                                    

SIRT2_HUMAN	RHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMI
1j8f		RHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMI
SSE		CCEECHHHHHHHHHCCCCCECCCCCCEEEEEECCECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHH
VARSPLIC	                                                                 RRRRRRDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

SIRT2_HUMAN	MGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTSASPKKSPPPAKDEARTTEREKPQ
1j8f		MGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQS---------------------------------
SSE		HHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC---------------------------------
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

Varsplic events:
VSP_008728 REMOVE 272-389, affected aminoacids in template: 227-311 Color: Red
VSP_008727 REPLACE 266-271 VQPFAS => GRGLAG, affected aminoacids in template: 221-226 Color: Green

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