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Alternative Splicing Gallery

Detail view for swissprot protein DNMT2_HUMAN and isoform O14717-5

Template: 1g55
Sequence Identity (Template - Swissprot): 1.0
Coverage of swissprot protein: 0.79539645

Alignment

DNMT2_HUMAN	MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFL
1g55		-EPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPP------------------NSFL
SSE		-CCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEECCCHHHCCHHHHHHHCCCEEEECCC------------------CHHH
VARSPLIC	                                                          RRRRRRRRRRRRRDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

DNMT2_HUMAN	HILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMD
1g55		HILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIEN-GFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPK------------
SSE		HHHHHHHHCCCCCCEEEEEEECCHHHCHHHHHHHHHHHH-CEEEEEEEECHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCEECCCCC------------
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

DNMT2_HUMAN	VENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSY
1g55		-----------------------------------------------LSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPT-RRSVCFTKGYGSY
SSE		-----------------------------------------------CCCCCHHHHCCCCCCHHHHECCHHHHHHHHHHCCEECCC-CCCCCCCCCCCCC
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

DNMT2_HUMAN	IEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE
1g55		IEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE
SSE		CCCCCCEEECCCCCCHHHHHHCCCCCCHHHHHHHHHCCCEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHC
VARSPLIC	DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD

Varsplic events:
VSP_005632 REPLACE 59-71 GITLEEFDRLSFD => ITKITKVYSFGKC, affected aminoacids in template: 57-69 Color: Green
VSP_005633 REMOVE 72-391, affected aminoacids in template: 70-310 Color: Red

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