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Alternative Splicing Gallery

Detail view for swissprot protein MK11_HUMAN and isoform Q15759-2

Template: 2ghl
Sequence Identity (Template - Swissprot): 0.75748503
Coverage of swissprot protein: 0.89784944

Alignment

MK11_HUMAN	MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFS
2ghl		----RPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGHRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFN
SSE		----CCCEEEEEECCEEEEEECCEEEEEEEEECCCEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCECCECCCCEEECCCCCCCCCC
VARSPLIC	                                                                                                    

MK11_HUMAN	EVYLVTTLMGADLNNIVKCQAGAHQGARLALDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPE
2ghl		DVYLVTHLMGADLNNIV-----------LT-DDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLAR----------ATRWYRAPE
SSE		CCEEEEECCCEECCCCC-----------CC-HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCEEECCCCCCC----------CHHHHCCHH
VARSPLIC	                            SS                                                                      

MK11_HUMAN	IMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLD
2ghl		IMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLAQMPKMNFANVFIGANPLAVDLLEKMLVLD
SSE		HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCC
VARSPLIC	                                                                                                    

MK11_HUMAN	SDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
2ghl		SDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP------------
SSE		CCCCCCHHHHHHCHHHCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCC------------
VARSPLIC

Varsplic events:
VSP_004841 REPLACE 122-131 GAHQGARLAL => LS, affected aminoacids in template: 113-114 Color: Pink

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